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Consistent with the current study, our groups have shown that LCDV1-VILP can also serve as an inhibitor of IGF1R in HEK293 cells, and using chimeric peptides of IGF-1 and LCDV1-VILP, shown that the C-peptide domain of the VILP is essential for its antagonistic action 29

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Sikiric et al., 2020a) may contrast with the miscellaneous underlying fistula causes, various origin and location and different occurrences (Visschers et al., 2012