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3.2 The Up-Stream Regulatory Mechanisms of Ferroptosis 3.2.1 System X c − The cystine-glutamate antiporter System X c − is a disulfide-linked heterodimer composed of a light chain XCT and a heavy chain 4F2, namely, substrate-specific subunit SLC7A11 and regulatory subunit SLC3A2 (Song et al., 2018
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