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Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione: Why low GSH and weak GSTs increase vulnerability Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction
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