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In logistic regression analysis, male patients (OR 0.41[CI 0.18, 0.97];P = 0.043) and vertebral artery sCeAD (OR 0.33 [CI 0.14, 0.78];P = 0.012) were less likely to have recanalization after a median of 6.9 years

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For research protocol design purposes, this suggests that 48 weeks may be an insufficient observation window to capture the full weight loss potential of retatrutide at the 12mg dose