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The most common approach: 1 ml water in a 5 mg vial → 5 mg/ml (5000 mcg/ml) 2 ml water in a 5 mg vial → 2.5 mg/ml (2500 mcg/ml) 1 ml water in a 2 mg Semaglutide vial → 2 mg/ml — a 0.5 mg dose = 25 units (U-100) The exact units to draw depend on your vial size, the water volume, and your dose

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Biochemical pharmacology 86 , 200–209, doi: 10.1016/j.bcp.2013.05.007 (2013)