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Healthcare providers are strongly encouraged to do all of the following: Complete a REMS-compliant education program offered by an accredited provider of continuing education (CE) or another education program that includes all the elements of the FDA Education Blueprint for Health Care Providers Involved in the Management or Support of Patients with Pain
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Sevoflurane [(F 3 C) 2 COCH 2 F] is a widely used anesthetic, which may lose HF in the anesthetic circuit to generate 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (Compound A), which is nephrotoxic to rats (Anders, 2005)
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