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The phase 3 data arrived later and from an unusual source: the REDEFINE 1 trial, which included a cagrilintide 2.4 mg monotherapy arm alongside CagriSema, semaglutide 2.4 mg and placebo across 3,417 adults with obesity or overweight and at least one comorbidity, without type 2 diabetes
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Chronic conditions with poor blood supply -- where the tissue needs ongoing support to rebuild vasculature -- fit this profile well
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